Basic information

Investigator: prof. MUDr. Jiří Horáček, Ph.D., FCMA
Main recipient: The Institute of Computer Science of the Czech Academy of Sciences 
Co-recipient: National Institute of Mental Health (NIMH), UK, CTU
Research period: 1/1/2024 - 30/06/2028
Total budget: 241,403,636.75 CZK
NIMH budget: 53,560,070.74 CZK
Supported by: Ministry of Education, Youth and Sports of the Czech Republic (MŠMT)

Annotation

The project focuses on the development of computational models of brain activity that capture the dynamics of the brain across various timescales. The goal of the project is to advance research in the field of applied computational neuroscience in the Czech Republic, particularly through conducting top-tier research, strengthening connections with leading international institutions, developing the human resources of the involved research teams, and enhancing their experimental and computational capacities.

The project consists of three research objectives. The application potential of the first objective lies in the development of efficient and flexible computational models of brain dynamics, allowing adaptation to specific application tasks. The second research objective focuses on further advancements in the applied field of brain state monitoring and prediction, such as monitoring tissue excitability in epilepsy and predicting seizures. The third research objective is centered on the use of computational models for interventions in brain dynamics, with potential applications in the design and optimization of brain stimulation therapies and personalized approaches to pharmacotherapy.

NIMH is involved in research objectives 2 and 3.